Abstract. von Willebrand factor (vWF) is a multimeric adhesive glycoprotein with one factor VIII binding site/subunit. Prior reports J Clin Invest. 16. 1937. 113.

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41316 GÖTEBORG. Scand J Clin Lab Invest 1986; Supp\181:1-74. 24. Ryle JA. The natural history von Willebrand Factor, Biological and Clinical. Advances, Pizzomunno, Vieste  av L Ekesbo · 2015 — VIII-relaterad antigen.

Omarbetat efter Nemeth et al. J Clin Invest.

von Willebrand disease (VWD) is one of the most common inherited bleeding disorders, with a prevalence of symptomatic disease of ∼1 in 10 000. J Clin Invest

1937. 113. Type 2B von Willebrand factor (VWF) is characterized by gain of function mutations in the A1 domain inducing a greater affinity for platelet GPIb, J Clin Invest.

Von Willebrand Disease is an inherited bleeding disorder that is caused by deficiency or dysfunction of Von Willebrand Factor (VWF). VWF is a plasma protein that mediates the initial adhesion of

105:699-701, 2000. Ruggeri, Z.M. Developing basic and clinical research on von Willebrand factor and von Willebrand disease.

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Hum Mutat 2014; 35:1033. Willebrand Invest AB. 5 likes. Willebrand Invest AB was founded in 2011 by Stefan Willebrand, to act as an equity partner for small start-up companies where capital and knowledge are required. Molecular basis of human von Willebrand disease: analysis of platelet von Willebrand factor mRNA. Proc Natl Acad Sci U S A. 1989 May; 86 (10):3723–3727.

ABSTRACT. Von Willebrand disease (vWD) is caused by quantitative or qualitative defects, or both, of the von Willebrand factor (vWF), a multimeric  (1985) Von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal von Willebrand factor. J Clin Invest 76:1522–1529.
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We have characterized Factor VIII coagulant protein, present in normal human plasma, that reacts with a specific human 125I-labeled anti-human VIII:C antigen Fab antibody fragment. Two major Factor VIII coagulant antigen populations were present. The first, approximately 85% of the total antigen, wa …

av A Broberg — J Clin Invest 1991;88:1346-1353. 8.